Journal of Reproductive Immunology
Volume 92, Issue 1 , Pages 1-7 , December 2011

In vitro human immunodeficiency virus and sperm cell interaction mediated by the mannose receptor

  • Walter Cardona-Maya

      Affiliations

    • Reproduction Group, University of Antioquia, Medellin, Colombia
    • Corresponding Author InformationCorresponding author at: Reproduction Group, University of Antioquia, Carrera 53 # 61-30, lab 534, Medellin, Colombia. Tel.: +57 4 2196470; fax: +57 4 2191072.
  • ,
  • Paula A. Velilla

      Affiliations

    • Immunovirology Group, University of Antioquia, Medellin, Colombia
  • ,
  • Carlos Julio Montoya

      Affiliations

    • Immunovirology Group, University of Antioquia, Medellin, Colombia
  • ,
  • Ángela Cadavid

      Affiliations

    • Reproduction Group, University of Antioquia, Medellin, Colombia
  • ,
  • María T. Rugeles

      Affiliations

    • Immunovirology Group, University of Antioquia, Medellin, Colombia

Received 16 March 2011 ,Revised 29 August 2011 ,Accepted 1 September 2011.

References 

  1. Areneta MR. HIV infection after artificial insemination. Nurs. Stand. 1995;9:15
  2. Ashida ER, Scofield VL. Lymphocyte major histocompatibility complex-encoded class II structures may act as sperm receptors. Proc. Natl. Acad. Sci. U. S. A. 1987;84:3395–3399
  3. Baccetti B, Benedetto A, Burrini AG, Collodel G, Ceccarini EC, Crisa N, et al. HIV-particles in spermatozoa of patients with AIDS and their transfer into the oocyte. J. Cell Biol. 1994;127:903–914
  4. Baccetti B, Benedetto A, Collodel G, Di Caro A, Garbuglia AR, Piomboni P. The debate on the presence of HIV-1 in human gametes. J. Reprod. Immunol. 1998;41:41–67
  5. Bagasra O, Farzadegan H, Seshamma T, Oakes JW, Saah A, Pomerantz RJ. Detection of HIV-1 proviral DNA in sperm from HIV-1-infected men. AIDS. 1994;8:1669–1674
  6. Bandivdekar AH, Velhal SM, Raghavan VP. Identification of CD4-independent HIV receptors on spermatozoa. Am. J. Reprod. Immunol. 2003;50:322–327
  7. Barboza JM, Medina H, Doria M, Rivero L, Hernandez L, Joshi NV. Use of atomic force microscopy to reveal sperm ultrastructure in HIV-patients on highly active antiretroviral therapy. Arch. Androl. 2004;50:121–129
  8. Benoff S. Carbohydrates and fertilization: an overview. Mol. Hum. Reprod. 1997;3:599–637
  9. Benoff S, Cooper GW, Hurley I, Napolitano B, Rosenfeld DL, Scholl GM, et al. Human sperm fertilizing potential in vitro is correlated with differential expression of a head-specific mannose-ligand receptor. Fertil. Steril. 1993;59:854–862
  10. Brogi A, Presentini R, Moretti E, Strazza M, Piomboni P, Costantino-Ceccarini E. New insights into the interaction between the gp120 and the HIV receptor in human sperm (human.sperm/gp120/galactoglycerolipid/antigalactosylceramide/seminolip id/spermatogonia). J. Reprod. Immunol. 1998;41:213–231
  11. Cardona-Maya WD, Cadavid AP. Evaluation of the role of the monosaccharides, mannose and N-acetylglucosamine in the induction of the acrosome reaction in human spermatozoa. Actas Urol. Esp. 2005;29:676–684
  12. Cardona-Maya W, Lopez-Herrera A, Velilla-Hernandez P, Rugeles MT, Cadavid AP. The role of mannose receptor on HIV-1 entry into human spermatozoa. Am. J. Reprod. Immunol. 2006;55:241–245
  13. Cardona-Maya W, Velilla P, Montoya CJ, Cadavid A, Rugeles MT. Presence of HIV-1 DNA in spermatozoa from HIV-positive patients: changes in the semen parameters. Curr. HIV Res. 2009;7:418–424
  14. Cardona Maya W, Rugeles MT, Cadavid AP. Interactions between human spermatozoids and human immunodeficiency virus. Actas Urol. Esp. 2009;33:223–226
  15. Ceballos A, Andreani G, Ayala SE, Romer Y, Rimoldi I, Agosti MR, et al. Epidemiological and molecular evidence of two events of father-to-child HIV type 1 horizontal transmission. AIDS Res. Hum. Retroviruses. 2004;20:789–793
  16. Ceballos A, Remes Lenicov F, Sabatte J, Rodriguez Rodrigues C, Cabrini M, Jancic C, et al. Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells. J. Exp. Med. 2009;206:2717–2733
  17. Chiasson MA, Stoneburner RL, Joseph SC. Human immunodeficiency virus transmission through artificial insemination. J. Acquir. Immune Defic. Syndr. 1990;3:69–72
  18. Douglas GC, Fry GN, Thirkill T, Holmes E, Hakim H, Jennings M, et al. Cell-mediated infection of human placental trophoblast with HIV in vitro. AIDS Res. Hum. Retroviruses. 1991;7:735–740
  19. Dussaix E, Guetard D, Dauguet C, D’almeida M, Auer J, Ellrodt A, et al. Spermatozoa as potential carriers of HIV. Res. Virol. 1993;144:487–495
  20. Eke AC, Oragwu C. Sperm washing to prevent HIV transmission from HIV-infected men but allowing conception in sero-discordant couples. Cochrane Database Syst. Rev. 2011;1:CD008498
  21. Fanibunda SE, Velhal SM, Raghavan VP, Bandivdekar AH. CD4 independent binding of HIV gp120 to mannose receptor on human spermatozoa. J. Acquir. Immune Defic. Syndr. 2008;48:389–397
  22. Harouse JM, Bhat S, Spitalnik SL, Laughlin M, Stefano K, Silberberg DH, et al. Inhibition of entry of HIV-1 in neural cell lines by antibodies against galactosyl ceramide. Science. 1991;253:320–323
  23. Hatsukari I, Singh P, Hitosugi N, Messmer D, Valderrama E, Teichberg S, et al. DEC-205-mediated internalization of HIV-1 results in the establishment of silent infection in renal tubular cells. J. Am. Soc. Nephrol. 2007;18:780–787
  24. Holmes N. Cd45: all is not yet crystal clear. Immunology. 2006;117:145–155
  25. Kim LU, Johnson MR, Barton S, Nelson MR, Sontag G, Smith JR, et al. Evaluation of sperm washing as a potential method of reducing HIV transmission in HIV-discordant couples wishing to have children. AIDS. 1999;13:645–651
  26. Liu Y, Liu H, Kim BO, Gattone VH, Li J, Nath A, et al. CD4-independent infection of astrocytes by human immunodeficiency virus type 1: requirement for the human mannose receptor. J. Virol. 2004;78:4120–4133
  27. Lusso P, Lori F, Gallo RC. CD4-independent infection by human immunodeficiency virus type 1 after phenotypic mixing with human T-cell leukemia viruses. J. Virol. 1990;64:6341–6344
  28. Nguyen DG, Hildreth JE. Involvement of macrophage mannose receptor in the binding and transmission of HIV by macrophages. Eur. J. Immunol. 2003;33:483–493
  29. Nuovo GJ, Becker J, Simsir A, Margiotta M, Khalife G, Shevchuk M. HIV-1 nucleic acids localize to the spermatogonia and their progeny. A study by polymerase chain reaction in situ hybridization. Am. J. Pathol. 1994;144:1142–1148
  30. Quinn TC, Wawer MJ, Sewankambo N, Serwadda D, Li C, Wabwire-Mangen F, et al. Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group. N. Engl. J. Med. 2000;342:921–929
  31. Salvatori F, De Martino M, Galli L, Vierucci A, Chieco-Bianchi L, De Rossi A. Horizontal transmission of human immunodeficiency virus type 1 from father to child. AIDS Res. Hum. Retroviruses. 1998;14:1679–1685
  32. Scofield V. Sperm as vectors and cofactors for HIV-1 transmission. J. NIH Res. 1992;4:108–111
  33. Scofield V. Sperm as infection-potentiating cofactors in HIV transmission. J. Reprod. Immunol. 1998;41:359–372
  34. Shattock RJ, Moore JP. Inhibiting sexual transmission of HIV-1 infection. Nat. Rev. Microbiol. 2003;1:25–34
  35. Stewart GJ, Tyler JP, Cunningham AL, Barr JA, Driscoll GL, Gold J, et al. Transmission of human T-cell lymphotropic virus type III (HTLV-III) by artificial insemination by donor. Lancet. 1985;2:581–585
  36. Trujillo JR, Rogers R, Molina RM, Dangond F, Mclane MF, Essex M, et al. Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor. Proc. Natl. Acad. Sci. U. S. A. 2007;104:5097–5102
  37. Wang D, Kang XJ, Li LB, Xie QD, Gao YS, Huang TH. In vitro study on vertical transmission of the HIV-1 gag gene by human sperm. J. Med. Virol. 2011;83:16–23
  38. WHO . WHO Laboratory Manual for the Examination of Human Semen and Sperm–Cervical Mucus Interaction. Cambridge: Cambridge University Press; 1999;
  39. Wolff H, Schill WB. Determination of sperm antibodies in human genital secretions by an ELISA technique. Hum. Reprod. 1988;3:223–225

PII: S0165-0378(11)00303-2

doi: 10.1016/j.jri.2011.09.002

Journal of Reproductive Immunology
Volume 92, Issue 1 , Pages 1-7 , December 2011