Journal of Reproductive Immunology
Volume 86, Issue 2 , Pages 122-125, November 2010

Soluble CD30 in normotensive pregnant women with isolated fetal intrauterine growth restriction: a comparison with preeclamptic women

  • Marzena Laskowska

      Affiliations

    • Department of Obstetrics and Perinatology, Medical University of Lublin, ul. Jaczewskiego 8, 20-950 Lublin, Poland
    • Corresponding Author InformationCorresponding author. Tel.: +48 81 7244841; fax: +48 81 7244841.
  • ,
  • Katarzyna Laskowska

      Affiliations

    • Department of Gastroenterology, Medical University of Lublin, ul. Jaczewskiego 8, 20-950 Lublin, Poland
  • ,
  • Jan Oleszczuk

      Affiliations

    • Department of Obstetrics and Perinatology, Medical University of Lublin, ul. Jaczewskiego 8, 20-950 Lublin, Poland

Received 28 December 2009; received in revised form 19 April 2010; accepted 16 May 2010. published online 15 June 2010.

Abstract 

This study investigated the serum concentration of soluble CD30 (sCD30) in pregnant women with isolated fetal intrauterine growth restriction, in pregnancies complicated by preeclampsia with and without accompanying intrauterine growth restriction, and in normotensive healthy pregnant controls. Lower serum concentrations of sCD30 were observed in the group of normotensive pregnant women with a growth-restricted fetus in comparison with the group of healthy pregnant controls, and also in comparison with both preeclamptic groups of pregnant women with and without fetal growth restriction. The concentration of sCD30 in maternal serum from preeclamptic women did not differ in comparison with values from healthy controls or pregnancies complicated by isolated fetal intrauterine growth restriction.

Keywords: sCD30, Intrauterine fetal growth restriction (IUGR), Preeclampsia

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PII: S0165-0378(10)00099-9

doi:10.1016/j.jri.2010.05.004

Journal of Reproductive Immunology
Volume 86, Issue 2 , Pages 122-125, November 2010