« Previous
Next »
Journal of Reproductive Immunology
Volume 83, Issue 1
, Pages 168-172
, December 2009
The role of the local microenvironment in regulating susceptibility and immune responses to sexually transmitted viruses in the female genital tract
References
- . Innate immunity at the mucosal surface: role of toll-like receptor 3 and toll-like receptor 9 in cervical epithelial cell responses to microbial pathogens. Biol. Reprod. 2006;74:824–831
- . Local delivery of CpG oligodeoxynucleotides induces rapid changes in the genital mucosa and inhibits replication, but not entry, of herpes simplex virus type 2. J. Virol. 2003;77:8948–8956
- . Transmission of HIV-1 by primary human uterine epithelial cells and stromal fibroblasts. J. Infect. Dis. 2004;190:236–245
- . Intranasal and subcutaneous immunization under the effect of estradiol leads to better protection against genital HSV-2 challenge compared to progesterone. Vaccine. 2008;26:6165–6172
- . Cell-free human immunodeficiency virus type 1 transcytosis through primary genital epithelial cells. J. Virol. 2007;81:395–405
- . Early events in HIV transmission through a human reconstructed vaginal mucosa. Aids. 2008;22:1257–1266
- . Interactions of female hormonal environment, susceptibility to viral infection and disease progression. AIDS Patient Care STDS. 2002;16:211–221
- . Microbial translocation is a cause of systemic immune activation in chronic HIV infection. Nat. Med. 2006;12:1365–1371
- Center for Disease Control and Prevention, C., 2009. Trends in Reportable sexually transmitted diseases in the United States, 2007. Available at: http://www.cdc.gov/std/stats07.
- . Recent observations on HIV type-1 infection in the genital tract of men and women. Aids. 2003;17:455–480
- . Genital Herpes. In: Holmes KK, Sparling PF, Mardh PA, Lemon SM, Stamm WE, Piot P, Wasserheit JN editor. Sexually Transmitted Diseases. third ed.. New York: McGraw-Hill; 1999;
- . Response to Neisseria gonorrhoeae by cervicovaginal epithelial cells occurs in the absence of Toll-like Receptor 4-mediated signaling. J. Immunol. 2002;168:2424–2432
- . Human cytomegalovirus and human immunodeficiency virus type-1 co-infection in human cervical tissue. Virology. 2007;369:55–68
- . DC-SIGN, a dendritic cell-specific HIV-1 binding protein that enhances trans-infection of T-cells. Cell. 2000;100:587–597
- . Prolonged exposure to progesterone prevents induction of protective mucosal responses following intravaginal immunization with attenuated herpes simplex virus type 2. J. Virol. 2003;77:9845–9851
- . Estradiol regulates susceptibility following primary exposure to genital herpes simplex virus type 2, while progesterone induces inflammation. J. Virol. 2005;79:3107–3116
- . Protection against genital herpes infection in mice immunized under different hormonal conditions correlates with induction of vagina-associated lymphoid tissue. J. Virol. 2005;79:3117–3126
- . Quantification of poly(I:C)-mediated protection against genital herpes simplex virus type 2 infection. J. Virol. 2006;80:9988–9997
- . Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1. Immunity. 2007;26:257–270
- . Chlamydia trachomatis infection in the female reproductive tract of rat: influence of progesterone on infectivity and immune response. Infect. Immun. 1998;66:893–898
- . Effect of estradiol and progesterone on susceptibility and immune responses to Chlamydia trachomatis infection in the female reproductive tract. Infect. Immun. 2000;68:4207–4216
- . Progesterone increases susceptibility and decreases immune responses to genital herpes infection. J. Virol. 2003;77:4558–4565
- . Hormonal contraception and risk of HIV-1 acquisition: results of a 10-year prospective study. Aids. 2004;18:695–697
- . An estimate of global prevalence and incidence of herpes simplex virus type 2 infection. Bull. World Health Organ. 2008;86:737–816
- . Susceptibility of human female primary genital epithelial cells to herpes simplex virus, type-2 and the effect of TLR3 ligand and sex hormones on infection. Biol. Reprod. 2007;77:1049–1059
- . HIV binding, penetration, and primary infection in human cervicovaginal tissue. Proc. Natl. Acad. Sci. U.S.A. 2005;102:11504–11509
- . Ex vivo modeling of oral HIV transmission in human palatine tonsil. J. Histochem. Cytochem. 2005;53:631–642
- . Innate immunity: the virtues of a nonclonal system of recognition. Cell. 1997;91:295–298
- . Target cells in vaginal HIV transmission. Microbes Infect. 2003;5:59–67
- . Depomedroxyprogesterone-induced hypoestrogenism and changes in vaginal flora and epithelium. Obstet. Gynecol. 2000;96:431–439
- Association of cervical ectopy with heterosexual transmission of human immunodeficiency virus: results of a study of couples in Nairobi, Kenya. J. Infect. Dis. 1991;164:588–591
- . Cervical shedding of herpes simplex virus in human immunodeficiency virus-infected women: effects of hormonal contraception, pregnancy, and vitamin A deficiency. J. Infect. Dis. 2000;181:58–63
- . Differential induction of innate anti-viral responses by TLR ligands against Herpes simplex virus, type 2, infection in primary genital epithelium of women. Antiviral Res. 2009;81:103–112
- . Vaginal immunity in the HSV-2 mouse model. Int. Rev. Immunol. 2003;22:43–63
- . Herpes simplex virus type 2: epidemiology and management options in developing countries. Sex Trans. Infect. 2007;83:16–22
- . Mechanism of HIV spread from lymphocytes to epithelia. Virology. 1992;186:261–273
- . Oral contraceptive use induces upregulation of CCR5 chemokine receptor in the cervical epithelium of healthy women. J. Reprod. Immunol. 2002;54:117–131
- . Immunological microenvironments in the human vagina and cervix: mediators of cellular immunity are concentrated in the cervical transformation zone. Biol. Reprod. 2005;73:1253–1263
- . The innate and early immune response to pathogen challenge in the female genital tract and the pivotal role of epithelial cells. J. Reprod. Immunol. 2002;57:61–79
- . Viral load and heterosexual transmission of HIV-1. Rakai project Study Group. N. Engl. J. Med. 2000;342:921–929
- . Innate immunity in the human female reproductive tract: antiviral response of uterine epithelial cells to the TLR3 agonist poly(I:C). J. Immunol. 2005;174:992–1002
- . gp340 expressed on human genital epithelia binds HIV-1 envelope protein and facilitates viral transmission. J. Immunol. 2007;179:3126–3132
- . CpG oligodeoxynucleotide augments HSV-2 glycoprotein D DNA vaccine efficacy to generate T helper 1 response and subsequent protection against primary genital herpes infection in mice. J. Reprod. Immunol. 2005;68:53–69
- . Diversity of receptors binding HIV on dendritic cell subsets. Nat. Immunol. 2002;3:975–983
- Unaids, 2008. UNAIDS Report on AIDS Epidemic, July 2008.
- . The effect of hormonal contraception on genital tract shedding of HIV-1. Aids. 2004;18:205–209
- . Role of sex hormones and cytokines in regulating mucosal immune system in the female reproductive tract. In: Ogra PL, Mestecky J, Lamm ME, Strober W, Bienenstock J, McGhee JR editor. Mucosal Immunity. second ed.. San Diego: Academic Press; 1999;
- . Epithelial cells in the female reproductive tract: a central role as sentinels of immune protection. Am. J. Reprod. Immunol. 2005;53:65–76
PII: S0165-0378(09)00472-0
doi: 10.1016/j.jri.2009.08.010
© 2009 Elsevier Ireland Ltd. All rights reserved.
« Previous
Next »
Journal of Reproductive Immunology
Volume 83, Issue 1
, Pages 168-172
, December 2009
