« Previous
Next »
Journal of Reproductive Immunology
Volume 83, Issue 1
, Pages 179-184
, December 2009
Chlamydial protease-like activity factor—insights into immunity and vaccine development
References
- . Transcutaneous immunization with combined cholera toxin and CpG adjuvant protects against Chlamydia muridarum genital tract infection. Infect. Immun. 2004;72:1019–1028
- . Immunology of Chlamydia infection: implications for a Chlamydia trachomatis vaccine. Nat. Rev. Immunol. 2005;5:149–161
- . Intranasal immunization with chlamydial protease-like activity factor and CpG deoxynucleotides enhances protective immunity against genital Chlamydia muridarum infection. Vaccine. 2007;25:3773–3780
- . Chlamydia trachomatis polymorphic membrane protein D is a species-common pan-neutralizing antigen. Proc. Natl. Acad. Sci. U.S.A. 2006;103:1894–1899
- . Cleavage-dependent activation of a Chlamydia-secreted protease. Mol. Microbiol. 2004;52:1487–1494
- . Cleavage of host keratin 8 by a Chlamydia-secreted protease. Infect. Immun. 2004;72:3863–3868
- . Production of a proteolytically active protein, chlamydial protease/proteasome-like activity factor, by five different Chlamydia species. Infect. Immun. 2005;73:1868–1872
- . Chlamydia pneumoniae secretion of a protease-like activity factor for degrading host cell transcription factors required for major histocompatibility complex antigen expression. Infect. Immun. 2002;70:345–349
- . Inhibition of apoptosis in Chlamydia-infected cells: blockade of mitochondrial cytochrome c release and caspase activation. J. Exp. Med. 1998;187:487–496
- . Structural basis for activation and inhibition of the secreted Chlamydia protease CPAF. Cell Host Microbe. 2008;4:529–542
- . Role for CD8+ T cells in antichlamydial immunity defined by Chlamydia-specific T-lymphocyte clones. Infect. Immun. 1994;62:5195–5197
- . Expression, processing, and localization of PmpD of Chlamydia trachomatis serovar L2 during the chlamydial developmental cycle. PLoS ONE. 2007;2:e568
- . Actin and intermediate filaments stabilize the Chlamydia trachomatis vacuole by forming dynamic structural scaffolds. Cell Host Microbe. 2008;4:159–169
- . Induction of cross-serovar protection against genital chlamydial infection by a targeted multisubunit vaccination approach. Clin. Vaccine Immunol. 2007;14:1537–1544
- . Antigen-specific CD4+ T cells produce sufficient IFN-gamma to mediate robust protective immunity against genital Chlamydia muridarum infection. J. Immunol. 2008;180:3375–3382
- . Role of CD8 T cells in primary Chlamydia infection. Infect. Immun. 1995;63:516–521
- . Immunity to murine Chlamydia trachomatis genital tract reinfection involves B cells and CD4+ T cells but not CD8+ T cells. Infect. Immun. 2000;68:6979–6987
- . Immunity to murine chlamydial genital infection. Infect. Immun. 2002;70:2741–2751
- . A predominant role for antibody in acquired immunity to chlamydial genital tract reinfection. J. Immunol. 2005;175:7536–7542
- . The protective efficacy of chlamydial protease-like activity factor vaccination is dependent upon CD4+ T cells. Cell. Immunol. 2006;242:110–117
- . Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele. Infect. Immun. 2006;74:6722–6729
- . Intranasal vaccination with a secreted chlamydial protein enhances resolution of genital Chlamydia muridarum infection, protects against oviduct pathology, and is highly dependent upon endogenous gamma interferon production. Infect. Immun. 2007;75:666–676
- . A limited role for antibody in protective immunity induced by rCPAF and CpG vaccination against primary genital Chlamydia muridarum challenge. FEMS Immunol Med Microbiol. 2009;55:271–279
- . Monoclonal immunoglobulin A antibody to the major outer membrane protein of the Chlamydia trachomatis mouse pneumonitis biovar protects mice against a chlamydial genital challenge. Vaccine. 1997;15:575–582
- . Vaccination with the Chlamydia trachomatis major outer membrane protein can elicit an immune response as protective as that resulting from inoculation with live bacteria. Infect. Immun. 2005;73:8153–8160
- . Immunization with the Chlamydia trachomatis major outer membrane protein, using adjuvants developed for human vaccines, can induce partial protection in a mouse model against a genital challenge. Vaccine. 2006;24:766–775
- . The secreted protease factor CPAF is responsible for degrading pro-apoptotic BH3-only proteins in Chlamydia trachomatis-infected cells. J. Biol. Chem. 2006;281:31495–31501
- . Resolution of chlamydial genital infection in B-cell-deficient mice and immunity to reinfection. Infect. Immun. 1988;56:1320–1325
- . Effect of gamma interferon on resolution of murine chlamydial genital infection. Infect. Immun. 1992;60:4427–4429
- . Epidemiology of chlamydial infection: are we losing ground?. Sex Transm. Infect. 2008;84:87–91
- . Proteomic analysis of Chlamydia pneumoniae-infected HL cells reveals extensive degradation of cytoskeletal proteins. FEMS Immunol. Med. Microbiol. 2008;54:375–384
- . Human antibody responses to a Chlamydia-secreted protease factor. Infect. Immun. 2004;72:7164–7171
- . Inhibition of proteolytic activity of a chlamydial proteasome/protease-like activity factor by antibodies from humans infected with Chlamydia trachomatis. Infect. Immun. 2005;73:4414–4419
- . Profiling of human antibody responses to Chlamydia trachomatis urogenital tract infection using microplates arrayed with 156 chlamydial fusion proteins. Infect. Immun. 2006;74:1490–1499
- . Characterization of a secreted Chlamydia protease. Cell. Microbiol. 2002;4:411–424
- . CD4+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract. Infect. Immun. 1995;63:3302–3308
- . Chlamydia trachomatis genital tract infection of antibody-deficient gene knockout mice. Infect. Immun. 1997;65:1993–1999
- . Chlamydia inhibits interferon gamma-inducible major histocompatibility complex class II expression by degradation of upstream stimulatory factor 1. J. Exp. Med. 1999;189:1931–1938
- . Degradation of transcription factor RFX5 during the inhibition of both constitutive and interferon gamma-inducible major histocompatibility complex class I expression in Chlamydia-infected cells. J. Exp. Med. 2000;191:1525–1534
- . Identification of a chlamydial protease-like activity factor responsible for the degradation of host transcription factors. J. Exp. Med. 2001;193:935–942
PII: S0165-0378(09)00467-7
doi: 10.1016/j.jri.2009.05.007
© 2009 Elsevier Ireland Ltd. All rights reserved.
« Previous
Next »
Journal of Reproductive Immunology
Volume 83, Issue 1
, Pages 179-184
, December 2009
