Journal of Reproductive Immunology
Volume 83, Issue 1 , Pages 45-49 , December 2009

The multifunctional zona pellucida and mammalian fertilization

  • Paul M. Wassarman

      Affiliations

    • Corresponding Author InformationCorresponding authors. Tel.: +1 212 241 8616; fax: +1 212 860 9279.
    • ,
  • Eveline S. Litscher

      Affiliations

    • Corresponding Author InformationCorresponding authors. Tel.: +1 212 241 8616; fax: +1 212 860 9279.

Received 18 December 2008 ,Revised 10 April 2009 ,Accepted 26 June 2009.

References 

  1. Bleil JD, Wassarman PM. Autoradiographic visualization of the mouse oocyte's sperm receptor bound to sperm. J. Cell Biol. 1986;102:1363–1371
  2. Chen J, Litscher ES, Wassarman PM. Inactivation of the mouse sperm receptor, mZP3, by site-directed mutagenesis of individual serine residues located at the combining-site for sperm. Proc. Natl. Acad. Sci. U.S.A. 1998;95:6193–6197
  3. Clark GF, Dell A. Molecular models for murine sperm-oocyte binding. J. Biol. Chem. 2006;281:13853–13856
  4. Dell A, Chalabi S, Easton RL, Haslam SM, Sutton-Smith M, Patankar MS, et al. Murine and human zona pellucida 3 derived from mouse oocytes express identical O-glycans. Proc. Natl. Acad. Sci. U.S.A. 2003;100:15631–15636
  5. Jovine L, Darie CC, Litscher ES, Wassarman PM. Zona pellucida domain proteins. Annu. Rev. Biochem. 2005;74:83–114
  6. Kinloch RA, Mortillo S, Stewart CL, Wassarman PM. Embryonal carcinoma cells transfected with ZP3 genes differentially glycosylate similar polypeptides and secrete active mouse sperm receptor. J. Cell Biol. 1991;115:655–664
  7. Kinloch RA, Mortillo S, Wassarman PM. Transgenic mouse oocytes with functional hamster sperm receptors in their zona pellucida. Development. 1992;115:937–946
  8. Kinloch RA, Sakai Y, Wassarman PM. Mapping the mouse ZP3 combining site for sperm by exon-swapping and site-directed mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 1995;92:263–267
  9. Litscher ES, Wassarman PM. Recombinant hamster sperm receptors that exhibit species-specific binding to sperm. Zygote. 1996;4:229–236
  10. Litscher ES, Janssen WG, Darie CC, Wassarman PM. Purified mouse oocyte zona pellucida glycoproteins polymerize into homomeric fibrils under non-denaturing conditions. J. Cell. Physiol. 2008;214:153–157
  11. Moller CC, Bleil JD, Kinloch RA, Wassarman PM. Structural and functional relationships between mouse and hamster zona pellucida glycoproteins. Dev. Biol. 1990;137:276–286
  12. Mortillo S, Wassarman PM. Differential binding of gold-labeled zona pellucida glycoproteins mZP2 and mZP3 to mouse sperm membrane compartments. Development. 1991;113:141–149
  13. Swanson WJ, Yang Z, Wolfner M, Aquadro CF. Positive Darwinian selection drives the evolution of several female reproductive proteins in mammals. Proc. Natl. Acad. Sci. U.S.A. 2001;98:2509–2514
  14. Wassarman PM. Zona pellucida glycoproteins. Annu. Rev. Biochem. 1988;57:415–442
  15. Wassarman PM. Mammalian fertilization: molecular aspects of gamete adhesion, exocytosis, and fusion. Cell. 1999;96:175–183
  16. Wassarman PM. Contribution of mouse oocyte zona pellucida glycoproteins to gamete recognition during fertilization. J. Cell. Physiol. 2005;204:388–391
  17. Wassarman PM. Zona pellucida glycoproteins. J. Biol. Chem. 2008;283:24285–24289
  18. Wassarman PM, Jovine L, Litscher ES. A profile of fertilization in mammals. Nature Cell Biol. 2001;3:E59–E64
  19. Williams Z, Litscher ES, Jovine L, Wassarman PM. Polypeptide encoded by mouse ZP3 exon-7 is necessary and sufficient for binding of mouse sperm in vitro. J. Cell. Physiol. 2006;207:30–39
  20. Yonezawa N, Kudo K, Terauchi H, Kanai S, Yoda N, Tanokura M, et al. Recombinant porcine zona pellucida glycoproteins expressed in Sf9 cells bind to bovine sperm but not to porcine sperm. J. Biol. Chem. 2005;280:20189–20196

PII: S0165-0378(09)00460-4

doi: 10.1016/j.jri.2009.06.259

Journal of Reproductive Immunology
Volume 83, Issue 1 , Pages 45-49 , December 2009

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