Journal of Reproductive Immunology
Volume 78, Issue 2 , Pages 149-157 , July 2008

Antibodies to two ZP3 B cell epitopes affect zona pellucida assembly

  • Jason Borillo

      Affiliations

    • Department of Diagnostic Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    • ,
  • Scott A. Coonrod

      Affiliations

    • Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    • ,
  • Jean Wu

      Affiliations

    • Department of Diagnostic Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    • ,
  • Cindy Zhou

      Affiliations

    • Department of Diagnostic Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    • ,
  • Yahuan Lou

      Affiliations

    • Department of Diagnostic Sciences, University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    • Corresponding Author InformationCorresponding author at: 3.108C DBB, Department of Diagnostic Sciences, University of Texas Health Science Center at Houston, 6516 M.D. Anderson Boulevard, Houston, TX 77030, USA. Tel.: +1 713 500 4059; fax: +1 713 500 4500.

Received 25 September 2007 ,Revised 29 December 2007 ,Accepted 6 February 2008.

References 

  1. Blake DA, Forsberg AS, Johansson BR, Wikland M. Laser zona pellucida thinning—an alternative approach to assisted hatching. Hum. Reprod. 2001;16:1959–1964
  2. Bronson RA, McLaren A. Transfer to the mouse oviduct of mouse eggs with and without the zona pellucida. J. Reprod. Fertil. 1970;22:129–137
  3. Epifano O, Liang LF, Familari M, Moos MC, Dean J. Coordinate expression of the three zona pellucida genes during mouse oogenesis. Development. 1995;121:1947–1956
  4. Gordon JW, Dapunt U. A new mouse model for embryos with a hatching deficiency and its use to elucidate the mechanism of blastocyst hatching. Fertil. Steril. 1993;59:1296–1301
  5. Hoodbhoy T, Aviles M, Baibakov B, Epifano O, Jimenez-Movilla M, Gauthier L, et al. ZP2 and ZP3 traffic independently within oocytes prior to assembly into the extracellular zona pellucida. Mol. Cell. Biol. 2006;26:7991–7998
  6. Jovine L, Qi H, Williams Z, Litscher ES, Wassarman PM. A duplicated motif controls assembly of zona pellucida domain proteins. Proc. Natl. Acad. Sci. U.S.A. 2004;101:5922–5927
  7. Kurotaki Y, Hatta K, Nakao K, Nabeshima Y, Fujimori T. Blastocyst axis is specified independently of early cell lineage but aligns with the ZP shape. Science. 2007;316:719–723
  8. Litscher ES, Wassarman PM. Egg extracellular coat proteins: from fish to mammals. Histol. Histopathol. 2007;22:337–347
  9. Lopata A, Hay DL. The potential of early human embryos to form blastocysts, hatch from their zona and secrete HCG in culture. Hum. Reprod. 1989;4(8 Suppl.):87–94
  10. Lou YH, Ang J, Thai H, McElveen F, Tung KS. A zona pellucida 3 peptide vaccine induces antibodies and reversible infertility without ovarian pathology. J. Immunol. 1995;155:2715–2720
  11. Lou YH, McElveen MF, Garza KM, Tung KS. Rapid induction of autoantibodies by endogenous ovarian antigens and activated T cells: implication in autoimmune disease pathogenesis and B cell tolerance. J. Immunol. 1996;156:3535–3540
  12. Lou YH, Takahashi H. Spermiogenesis in the Tilapia Oreochromis niloticus with notes on a unique pattern of unclear chromatin condensation. J. Morphol. 1989;200:321-320
  13. Matzuk MM, Burns KH, Viveiros MM, Eppig JJ. Intercellular communication in the mammalian ovary: oocytes carry the conversation. Science. 2002;296:2178–2180
  14. Millar SE, Chamow SM, Baur AW, Oliver C, Robey F, Dean J. Vaccination with a synthetic zona pellucida peptide produces long-term contraception in female mice. Science. 1989;246:935–938
  15. Naz RK, Gupta SK, Gupta JC, Vyas HK, Talwar AG. Recent advances in contraceptive vaccine development: a mini-review. Hum. Reprod. 2005;20:3271–3383
  16. Qi H, William Z, Wassarman PM. Secretion and assembly of zona pellucida glycoproteins by growing mouse oocytes microinjected with epitope-tagged cDNAs from mZP2 and mZP3. Mol. Biol. Cell. 2002;13:530–541
  17. Rankin TL, O’Brien M, Lee E, Wigglesworth K, Eppig J, Dean J. Defective zonae pellucidae in Zp2-null mice disrupt folliculogenesis, fertility and development. Development. 2001;128:1119–1126
  18. Rhim SH, Millar SE, Robey F, Luo AM, Lou YH, Yule T, et al. Autoimmune disease of the ovary induced by a ZP3 peptide from the mouse zona pellucida. J. Clin. Invest. 1992;89:28–35
  19. Sacco AG. Zona pellucida: current status as a candidate antigen for contraceptive vaccine development. Am. J. Reprod. Immunol. 1987;15:122–130
  20. Shivers CA, Dunbar BS. Autoantibodies to zona pellucida: a possible cause for infertility in women. Science. 1977;197:1082–1084
  21. Wassarman PM. The biology and chemistry of fertilization. Science. 1987;235:553–560
  22. Wood DM, Liu C, Dunbar BS. Effect of alloimmunization and heteroimmunization with zonae pellucidae on fertility in rabbits. Biol. Reprod. 1981;25:439–450
  23. Zhao M, Dean J. The zona pellucida in folliculogenesis, fertilization and early development. Rev. Endocr. Metab. Disord. 2002;3:19–26
  24. Zhou C, Borillo J, Wu J, Torres L, Lou YH. Ovarian expression of chemokines and their receptors. J. Reprod. Immunol. 2004;63:1–9

PII: S0165-0378(08)00023-5

doi: 10.1016/j.jri.2008.02.002

Journal of Reproductive Immunology
Volume 78, Issue 2 , Pages 149-157 , July 2008

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